{"id":8324,"date":"2021-07-28T10:10:46","date_gmt":"2021-07-28T08:10:46","guid":{"rendered":"https:\/\/filinf.it\/?page_id=8324"},"modified":"2024-02-23T16:48:42","modified_gmt":"2024-02-23T15:48:42","slug":"hodgkins-lymphoma","status":"publish","type":"page","link":"https:\/\/filinf.it\/en\/structure\/scientific-commission\/hodgkins-lymphoma\/","title":{"rendered":"Hodgkin&#8217;s lymphoma Commission"},"content":{"rendered":"<p><span data-contrast=\"none\"><a href=\"https:\/\/filinf.it\/en\/about-limphomas\/hodgkin-lymphoma-hl\/\">Hodgkin&#8217;s lymphoma<\/a> (HL) is a neoplasm of the\u00a0<\/span><b><span data-contrast=\"none\">lymphatic system<\/span><\/b><span data-contrast=\"none\">, which arises in the lymphatic tissues and organs (lymph nodes, spleen, bone marrow) and affects the cells (lymphocytes) which have the task of defending the body from infections, from the external agents and from the same neoplastic diseases. The name of the disease is the surname of Sir Thomas Hodgkin who described the disease in 1832.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><img fetchpriority=\"high\" decoding=\"async\" class=\"aligncenter size-full wp-image-5827\" src=\"https:\/\/filinf.it\/wp-content\/uploads\/2017\/02\/Cell-HL.png\" alt=\"\" width=\"446\" height=\"233\" srcset=\"https:\/\/filinf.it\/wp-content\/uploads\/2017\/02\/Cell-HL.png 446w, https:\/\/filinf.it\/wp-content\/uploads\/2017\/02\/Cell-HL-300x157.png 300w\" sizes=\"(max-width: 446px) 100vw, 446px\" title=\"\"><\/p>\n<p><span data-contrast=\"none\">The primary\u00a0<\/span><b><span data-contrast=\"none\">goal\u00a0<\/span><\/b><span data-contrast=\"none\">of the <strong>Hodgkin&#8217;s lymphoma Commission<\/strong> is to optimize the management of patients with H<\/span><span data-contrast=\"none\">L<\/span><span data-contrast=\"none\">\u00a0during the phases of first diagnosis and of replace and refractoriness of the disease through the creation of prospective studies and retrospective collections of &#8216;real life&#8217; data, involving the largest number of Centers that take care of these patients in Italy.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">This goal will be pursued through the development and approval of national and international\u00a0<\/span><b><span data-contrast=\"none\">study proposals<\/span><\/b><span data-contrast=\"none\">, aimed at comparing\u00a0<\/span><b><span data-contrast=\"none\">standard therapies with innovative therapeutic strategies in Hodgkin&#8217;s lymphoma<\/span><\/b><span data-contrast=\"none\">.<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<p><span data-contrast=\"none\">The proposals are:<\/span><span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/p>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\"><span data-contrast=\"none\">Design and start a randomized therapy trial for patients with advanced H<\/span><span data-contrast=\"none\">L<\/span><span data-contrast=\"none\">. In this way, it is possible expand previous FIL experiences towards potential improvement of the ABVD scheme;<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" aria-setsize=\"-1\" data-aria-posinset=\"2\" data-aria-level=\"1\"><span data-contrast=\"none\">Design and start phase II and phase I-II studies for patients with refractory and relapsed disease to test the safety and efficacy of new molecules active in this type of patient;<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" aria-setsize=\"-1\" data-aria-posinset=\"3\" data-aria-level=\"1\"><span data-contrast=\"none\">Shorten the time gap between preclinical screening of new molecules on in vitro H<\/span><span data-contrast=\"none\">L<\/span><span data-contrast=\"none\">\u00a0cell systems and clinical development through phase I and phase I-II studies;<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" aria-setsize=\"-1\" data-aria-posinset=\"4\" data-aria-level=\"1\"><span data-contrast=\"none\">Understand the management patterns of patients with refractory and relapse disease after the failure of allogeneic procedures through retrospective &#8220;real life&#8221; studies;<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" aria-setsize=\"-1\" data-aria-posinset=\"5\" data-aria-level=\"1\"><span data-contrast=\"none\">Collaborate with the\u00a0<\/span><span data-contrast=\"none\">Elderly<\/span><span data-contrast=\"none\">\u00a0Commission for studies in advanced age patients with H<\/span><span data-contrast=\"none\">L<\/span><span data-contrast=\"none\">\u00a0and with the Radiotherapy and Imaging \/ RIT Commissions for all proposed studies;<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"1\" aria-setsize=\"-1\" data-aria-posinset=\"5\" data-aria-level=\"1\"><span data-contrast=\"none\">Participate and collaborate with International Cooperative groups in prospective clinical studies.<\/span><span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335559739&quot;:160,&quot;335559740&quot;:259}\">\u00a0<\/span><\/li>\n<\/ul>\n","protected":false},"excerpt":{"rendered":"<p>Hodgkin&#8217;s lymphoma (HL) is a neoplasm of the\u00a0lymphatic system, which arises in the lymphatic tissues and organs (lymph nodes, spleen,&#8230;<\/p>\n","protected":false},"author":10007,"featured_media":9162,"parent":6944,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"acf":[],"_links":{"self":[{"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/pages\/8324"}],"collection":[{"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/users\/10007"}],"replies":[{"embeddable":true,"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/comments?post=8324"}],"version-history":[{"count":0,"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/pages\/8324\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/pages\/6944"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/media\/9162"}],"wp:attachment":[{"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/media?parent=8324"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}