{"id":6966,"date":"2018-08-06T10:02:37","date_gmt":"2018-08-06T08:02:37","guid":{"rendered":"https:\/\/filinf.it\/?page_id=6966"},"modified":"2025-01-20T11:55:33","modified_gmt":"2025-01-20T10:55:33","slug":"biological-studies","status":"publish","type":"page","link":"https:\/\/filinf.it\/en\/structure\/scientific-commission\/biological-studies\/","title":{"rendered":"Biological and Bioinformatics Studies Commission"},"content":{"rendered":"<p>The integration of\u00a0<b>biological studies<\/b>\u00a0in research projects on <a href=\"https:\/\/filinf.it\/en\/about-limphomas\/diagnosis\/\">diagnosis<\/a> and <a href=\"https:\/\/filinf.it\/en\/about-limphomas\/therapies\/\">therapy<\/a> of <a href=\"https:\/\/filinf.it\/en\/about-limphomas\/\">lymphomas<\/a>\u00a0is of fundamental importance to:<span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/p>\n<ul>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"25\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\">better understand the biological basis of lymphomas;<span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"25\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\">identify groups of patients at higher risk of recurrence;<\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"25\" aria-setsize=\"-1\" data-aria-posinset=\"2\" data-aria-level=\"1\">identify patients who may benefit most from targeted biological therapies;<span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"\uf0b7\" data-font=\"Symbol\" data-listid=\"25\" aria-setsize=\"-1\" data-aria-posinset=\"3\" data-aria-level=\"1\">identify individuals potentially susceptible of greater toxicity to the treatment.<span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/li>\n<\/ul>\n<p style=\"text-align: center;\"><img fetchpriority=\"high\" decoding=\"async\" class=\"alignnone\" title=\"Biological Studies\" src=\"https:\/\/filinf.it\/wp-content\/uploads\/2009\/12\/iStock_000051237470-640.jpg\" alt=\"Biological Studies\" width=\"640\" height=\"426\" \/><\/p>\n<p style=\"text-align: justify;\"><span class=\"TextRun SCXW131404941\" lang=\"EN-US\" xml:lang=\"EN-US\"><span class=\"NormalTextRun SCXW131404941\">FIL,<\/span><\/span><span class=\"TextRun SCXW131404941\" lang=\"EN-US\" xml:lang=\"EN-US\"><span class=\"NormalTextRun SCXW131404941\">\u00a0since the beginning of its history<\/span><\/span><span class=\"TextRun SCXW131404941\" lang=\"EN-US\" xml:lang=\"EN-US\"><span class=\"NormalTextRun SCXW131404941\">,<\/span><\/span><span class=\"TextRun SCXW131404941\" lang=\"EN-US\" xml:lang=\"EN-US\"><span class=\"NormalTextRun SCXW131404941\">\u00a0has always been characterized by a special focus on bi<\/span><\/span><span class=\"TextRun SCXW131404941\" lang=\"EN-US\" xml:lang=\"EN-US\"><span class=\"NormalTextRun SCXW131404941\">ological aspects. In particular, FIL\u00a0<\/span><\/span><span class=\"TextRun SCXW131404941\" lang=\"EN-US\" xml:lang=\"EN-US\"><span class=\"NormalTextRun SCXW131404941\">studies are at the forefront\u00a0<\/span><\/span><span class=\"TextRun SCXW131404941\" lang=\"EN-US\" xml:lang=\"EN-US\"><span class=\"NormalTextRun SCXW131404941\">in the<\/span><\/span><span class=\"TextRun SCXW131404941\" lang=\"EN-US\" xml:lang=\"EN-US\"><span class=\"NormalTextRun SCXW131404941\">\u00a0use of\u00a0<\/span><\/span><strong><span class=\"TextRun SCXW131404941\" lang=\"EN-US\" xml:lang=\"EN-US\"><span class=\"NormalTextRun SCXW131404941\">technologies for the assessment of minimal residual disease<\/span><\/span><span class=\"TextRun SCXW131404941\" lang=\"EN-US\" xml:lang=\"EN-US\"><span class=\"NormalTextRun SCXW131404941\">\u00a0(MRD)<\/span><\/span><\/strong><span class=\"TextRun SCXW131404941\" lang=\"EN-US\" xml:lang=\"EN-US\"><span class=\"NormalTextRun SCXW131404941\">, or to identify the persistence of the smallest amount of tumor cells in subjects in apparent complete remission. The presence of these cells represents a very important prognostic factor for identifying patients at high risk of recurrence<\/span><\/span><span class=\"TextRun SCXW131404941\" lang=\"EN-US\" xml:lang=\"EN-US\"><span class=\"NormalTextRun SCXW131404941\">.<\/span><\/span><span class=\"EOP SCXW131404941\" data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/p>\n<p>The <strong>objectives<\/strong> of <strong>Biological Studies Commission<\/strong> are:<span data-ccp-props=\"{&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/p>\n<ol>\n<li data-leveltext=\"%1.\" data-font=\"\" data-listid=\"27\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\">Develop, encourage and approve proposals for integrated biological studies to clinical trials;<span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"%1.\" data-font=\"\" data-listid=\"27\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\">Develop and support the conduct of studies on the MRD integrated clinical studies through the &#8220;<a href=\"https:\/\/filinf.it\/en\/mrd-network\/\">FIL MRD Network&#8221;<\/a> and constitute the formal representation of the same within the FIL;<span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"%1.\" data-font=\"\" data-listid=\"27\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\">Help getting through the &#8220;FIL MRD Network&#8221; harmonization and quality control of valuation techniques of minimal residual disease in lymphomas;<span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"%1.\" data-font=\"\" data-listid=\"27\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\">Further develop &#8220;networks&#8221; of biological similar to &#8220;FIL MRD Network&#8221; to promote biological research applied to clinical trials;<span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"%1.\" data-font=\"\" data-listid=\"27\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\">Interacting with the Commission Pathologists and other Commissions to improve the research activities of the Foundation;<span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/li>\n<li data-leveltext=\"%1.\" data-font=\"\" data-listid=\"27\" aria-setsize=\"-1\" data-aria-posinset=\"1\" data-aria-level=\"1\">Interacting with others\u00a0commission to promote the integration of clinical and biological elements of &#8220;precision medicine&#8221; in\u00a0FIL\u00a0clinical trials.<span data-ccp-props=\"{&quot;134233279&quot;:true,&quot;201341983&quot;:0,&quot;335551550&quot;:6,&quot;335551620&quot;:6,&quot;335559739&quot;:200,&quot;335559740&quot;:276}\">\u00a0<\/span><\/li>\n<\/ol>\n","protected":false},"excerpt":{"rendered":"<p>The integration of\u00a0biological studies\u00a0in research projects on diagnosis and therapy of lymphomas\u00a0is of fundamental importance to:\u00a0 better understand the biological&#8230;<\/p>\n","protected":false},"author":10003,"featured_media":0,"parent":6944,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":[],"acf":[],"_links":{"self":[{"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/pages\/6966"}],"collection":[{"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/users\/10003"}],"replies":[{"embeddable":true,"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/comments?post=6966"}],"version-history":[{"count":0,"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/pages\/6966\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/pages\/6944"}],"wp:attachment":[{"href":"https:\/\/filinf.it\/en\/wp-json\/wp\/v2\/media?parent=6966"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}